Free Pharma E Books » Spectroscopy

Pharmaceutical Analysis: A Textbook For Pharmacy Students And Pharmaceutical Chemists.

Admin — Mon, 21 Sep 2009 11:34:56 +0000

An introductory text, written with the needs of the student in mind, which explains all the most important techniques used in the analysis of pharmaceuticals – a key procedure in ensuring the quality of drugs .

The text is enhanced throughout with key points and self-assessment boxes, to aid student learning.

Chapter 1: Control of the quality of analytical methods
Chapter 2: Physical and chemical properties of drug molecules
Chapter 3: Titrimetic and chemical analysis methods
Chapter 4: Ultraviolet and visible spectroscopy
Chapter 5: Infrared spectrophotometry
Chapter 6: Atomic spectrophotometry
Chapter 7: Molecular emission spectroscopy
Chapter 8: Nuclear magnetic resonance spectroscopy
Chapter 9: Mass spectrometry
Chapter 10: Chromatographic theory
Chapter 11: Gas chromatography
Chapter 12: High pressure liquid chromatography
Chapter 13: Thin layer chromatography
Chapter 14: High performance capillary electrophoresis
Chapter 15: Extraction methods in pharmaceutical analysis

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http://rapidshare.com/files/195883823/Pharmaceutical_analysis_by_David_G_Watson.pdf

A complete introduction to Modren NMR spectroscopy.

Admin — Mon, 21 Sep 2009 11:30:28 +0000

Clear, accessible coverage of modern NMR spectroscopy-for students and professionals in many fields of science

Nuclear magnetic resonance (NMR) spectroscopy has made quantum leaps in the last decade, becoming a staple tool in such divergent fields as chemistry, physics, materials science, biology, and medicine. That is why it is essential that scientists working in these areas be fully conversant with current NMR theory and practice.

This down-to-basics text offers a comprehensive, up-to-date treatment of the fundamentals of NMR spectroscopy. Using a straightforward approach that develops all concepts from a rudimentary level without using heavy mathematics, it gives readers the knowledge they need to solve any molecular structure problem from a complete set of NMR data. Topics are illustrated throughout with hundreds of figures and actual spectra. Chapter-end summaries and review problems with answers are included to help reinforce and test understanding of key material.

From NMR studies of biologically important molecules to magnetic resonance imaging, this book serves as an excellent all-around primer on NMR spectroscopic analysis.

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http://rapidshare.com/files/197708252/A_Complete_Introduction_to_Modern_NMR_Spectroscopy.pdf

Introduction to Spectroscopy.

Admin — Mon, 21 Sep 2009 11:27:09 +0000

This comprehensive resource provides an unmatched systematic introduction to spectra and basic theoretical concepts in spectroscopic methods that create a practical learning resource whether you’re an introductory student or someone who needs a reliable reference text on spectroscopy.This well-rounded introduction features updated spectra; a modernized presentation of one-dimensional nuclear magnetic resonance (NMR) spectroscopy; the introduction of biological molecules in mass spectrometry; and inclusion of modern techniques alongside DEPT, COSY, and HECTOR. Count on this book’s exceptional presentation to provide the comprehensive coverage you need to understand today’s spectroscopic techniques.

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http://rapidshare.com/files/197713926/Introduction_to_Spectroscopy.pdf

Molecular Spectroscopy: Ira N. Levin

Admin — Mon, 21 Sep 2009 11:24:10 +0000

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http://rapidshare.com/files/199562095/MOLECULAR_SPECTROSCOPY_-_IRA_N._LEVINE.djvu

Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods [ILLUSTRATED]

Admin — Mon, 21 Sep 2009 11:21:57 +0000

Nuclear magnetic resonance (NMR) has become the chemist’s most general structural tool. It is one of the few techniques that may be applied to all three states of matter. Some spectra may be obtained from less than a microgram of material. In the early 1960s, spectra were taken crudely on strip-chart recorders. The field has since seen one major advance after another, culminating in the Nobel prizes awarded to Richard R. Ernst in 1991 and to Kurt Wuthrich in 2002. The very richness of the field, however, has made it intimidating to many users. How can they take full advantage of the power of the method when so much of the methodology seems to be highly technical, beyond the grasp of the casual user? This text was written to answer this question. The chapters provide an essentially nonmathematical introduction to the entire field, with emphasis on structural analysis.

The early chapters introduce classical NMR spectroscopy. A thorough understanding of proton and carbon chemical shifts (Chapter 3) is required in order to initiate any analysis of spectra. The role of other nuclei is key to the examination of molecules containing various heteroatoms. An analysis of coupling constants (Chapter 4) provides information about stereochemistry and connectivity relationships between nuclei. The older concepts of chemical shifts and coupling constants are emphasized, because they provide the basis for the application of modern pulse sequences.

Chapter 5 and 6 describe the basics of modern NMR spectroscopy. The phenomena of relaxation, of chemical dynamics, and of multiple resonance are considered thoroughly. One-dimensional multipulse sequences are explored to determine the number of protons attached to carbon atoms, to enhance spectral sensitivity, and to determine connectivities among carbon atoms. Concepts that have been considered advanced, but are now moving towards the routine, are examined, including phase cycling, composite pulses, pulsed field gradients, and shaped pulses. Two-dimensional methods represent the current apex of the field. We discuss a large number of these experiments. It is our intention to describe not only what the pulse sequences do, but also how they work, so that the user has a better grasp of the techniques.

Two chapters are dedicated to experimental methodologies. Although many people are provided with spectra by expert technicians, increasing numbers of chemists must record spectra themselves. They must consider and optimize numerous experimental variables. These chapters address not only the basic parameters, such as spectral width and acquisition time, but also the parameters of more advanced techniques, such as spectral editing and twodimensional spectra.

To summarize modern NMR spectroscopy, Chapter 8 carries out the total structural proof of a single complex natural product. This chapter illustrates the tactics and strategies of structure elucidation, from one-dimensional assignments to two-dimensional spectral correlations, culminating in stereochemical analysis based on Overhauser effects.

The theory behind NMR not only is beautiful in itself, but also offers considerable insight into the methodology. Consequently, a series of appendices presents a full treatment of this theoretical underpinning, necessary to the physical or analytical chemist, but possibly still edifying to the synthetic organic or inorganic chemist.

This text thus offers

* classical analysis of chemical shifts and coupling constants for both protons and other nuclei,
* modern multipulse and multidimensional methods, both explained and illustrated,
* experimental procedures and practical advice relative to the execution of NMR experiments,
* a chapter-long worked-out problem that illustrates the application of nearly all current methods to determine the structure and stereochemistry of a complex natural product,
* appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams, and
* extensive problems throughout the book.

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http://rapidshare.com/files/199563295/Nuclear_Magnetic_Resonance_Spectroscopy_An_introduction_To_Principles_Applications_and_experimental_

Raman Spectroscopy for Chemical Analysis

Admin — Mon, 21 Sep 2009 11:19:09 +0000

Owing to its unique combination of high information content and ease of use, Raman spectroscopy, which uses different vibrational energy levels to excite molecules (as opposed to light spectra), has attracted much attention over the past fifteen years. This book covers all aspects of modern Raman spectroscopy, including its growing use in both the laboratory and industrial analysis.

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http://rapidshare.com/files/199564668/Raman_Spectroscopy_for_Chemical_Analysis_-_RICHARD_L._McCREERY.pdf

Handbook of Spectroscopy, 2 Volumes

Admin — Mon, 21 Sep 2009 11:16:36 +0000

This handbook provides a straightforward introduction to the field, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that can be derived from spectra. The sequence of chapters covers the whole range of the electromagnetic spectrum, and the physical processes involved, from nuclear phenomena to molecular rotation processes.

* A day-by-day laboratory guide: its design based on 300 questionnaires filled-out by spectroscopists at universities, industries and research institutes
* A well-structured information source containing 5 methods and 5 applications sections framed by sections on general topics
* Guides users to a decision about which spectroscopic method and which instrumentation will be the most appropriate to solve their own practical problem
* A time- and cost-saving reference: data tables provide the comparison of different methods in a standardized form
* Rapid access to essential information
* Correct analysis of a huge number of measured spectra data and smart use of such information sources as databases and spectra libraries

In short, a spectroscopist´s dream come true.

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http://rapidshare.com/files/……………/HOS.rar

Introduction to Spectroscopy 3rd Edition

Admin — Mon, 21 Sep 2009 11:12:54 +0000

Covering important spectroscopic techniques used in the study of organic chemistry, this third edition is suitable to be used as the main text in a spectroscopy course, or as a supplement in a second year organic chemistry course. The text covers high resolution 300-MHz NMR spectra which replaces the older 60-MHz spectra. There is a survey section on 1H-NMR which provides a qualitative treatment of spectra by functional group, as well as a discussion on cross polarization in the 13C-NMR spectra and a “How to Solve Mass Spectrometry Problems” section.

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http://rapidshare.com/files/………………/ITS3RDED.rar